IL-4 Haplotype -590T, -34T and Intron-3 VNTR R2 Is Associated with Reduced Malaria Risk among Ancestral Indian Tribal Populations

BACKGROUND: Interleukin 4 (IL-4) is an anti-inflammatory cytokine, which regulates balance between T(H)1 and T(H)2 immune response, immunoglobulin class switching and humoral immunity. Polymorphisms in this gene have been reported to affect the risk of infectious and autoimmune diseases. METHODS: We...

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Main Authors: Jha, Aditya Nath, Singh, Vipin Kumar, Kumari, Namrata, Singh, Ashish, Antony, Justin, van Tong, Hoang, Singh, Sakshi, Pati, Sudhanshu S., Patra, Pradeep K., Singh, Rajender, Toan, Nguyen L., Song, Le H., Assaf, Amal, Messias–Reason, Iara J. T., Velavan, Thirumalaisamy P., Singh, Lalji, Thangaraj, Kumarasamy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480467/
https://ncbi.nlm.nih.gov/pubmed/23110190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048136
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