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IL-4 Haplotype -590T, -34T and Intron-3 VNTR R2 Is Associated with Reduced Malaria Risk among Ancestral Indian Tribal Populations

BACKGROUND: Interleukin 4 (IL-4) is an anti-inflammatory cytokine, which regulates balance between T(H)1 and T(H)2 immune response, immunoglobulin class switching and humoral immunity. Polymorphisms in this gene have been reported to affect the risk of infectious and autoimmune diseases. METHODS: We...

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Dades bibliogràfiques
Autors principals: Jha, Aditya Nath, Singh, Vipin Kumar, Kumari, Namrata, Singh, Ashish, Antony, Justin, van Tong, Hoang, Singh, Sakshi, Pati, Sudhanshu S., Patra, Pradeep K., Singh, Rajender, Toan, Nguyen L., Song, Le H., Assaf, Amal, Messias–Reason, Iara J. T., Velavan, Thirumalaisamy P., Singh, Lalji, Thangaraj, Kumarasamy
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480467/
https://ncbi.nlm.nih.gov/pubmed/23110190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048136
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