ATF6alpha Promotes Astroglial Activation and Neuronal Survival in a Chronic Mouse Model of Parkinson’s Disease

Accumulating evidence suggests a crucial role for the unfolded protein response (UPR) in Parkinson’s disease (PD). In this study, we investigated the relevance of the UPR in a mouse model of chronic MPTP/probenecid (MPTP/P) injection, which causes severe and persistent degeneration of dopaminergic n...

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Detalhes bibliográficos
Main Authors: Hashida, Koji, Kitao, Yasuko, Sudo, Hirofumi, Awa, Yoshitaka, Maeda, Shinichiro, Mori, Kazutoshi, Takahashi, Ryosuke, Iinuma, Munekazu, Hori, Osamu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480445/
https://ncbi.nlm.nih.gov/pubmed/23112876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047950
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