Temperature-Sensitive Mutant of Coxsackievirus B3 Establishes Resistance in Neonatal Mice That Protects Them During Adolescence Against Coxsackievirus B3-Induced Myocarditis

Inoculation of neonatal CD-1 mice by multiple routes with an amyocarditic temperature-sensitive (ts) mutant (ts 1) derived from a myocarditic parent variant of coxsackievirus B3 (CVB3(m)) resulted in approximately half of the neonates surviving to adolescence. Challenge of the ts 1 survivors with CV...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Gauntt, Charles J., Paque, Ronald E., Trousdale, Melvin D., Gudvangen, Richard J., Barr, David T., Lipotich, George J., Nealon, Timothy J., Duffey, Paul S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1983
Assuntos:
Viral Infections and Immunity
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348027/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6299950/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.39.2.851-864.1983
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