Integrative functional genomics identifies RINT1 as a novel GBM oncogene

Large-scale cancer genomics efforts are identifying hundreds of somatic genomic alterations in glioblastoma (GBM). Distinguishing between active driver and neutral passenger alterations requires functional assessment of each gene; therefore, integrating biological weight of evidence with statistical...

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Hlavní autoři: Quayle, Steven N., Chheda, Milan G., Shukla, Sachet A., Wiedemeyer, Ruprecht, Tamayo, Pablo, Dewan, Robert W., Zhuang, Li, Huang-Hobbs, Emmet, Haidar, Sam, Xiao, Yonghong, Ligon, Keith L., Hahn, William C., Chin, Lynda
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
Témata:
Basic and Translational Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480269/
https://ncbi.nlm.nih.gov/pubmed/23074196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos246
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