Short range exosomal transfer of viral RNA from infected cells to plasmacytoid dendritic cells triggers innate immunity

Viral nucleic acids often trigger an innate immune response in infected cells. Many viruses, including hepatitis C virus (HCV), have evolved mechanisms to evade intracellular recognition. Nevertheless, HCV-permissive cells can trigger a viral RNA-, TLR7- and cell contact-dependent compensatory inter...

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Bibliographic Details
Main Authors: Dreux, Marlène, Garaigorta, Urtzi, Boyd, Bryan, Décembre, Elodie, Chung, Josan, Whitten-Bauer, Christina, Wieland, Stefan, Chisari, Francis V.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479672/
https://ncbi.nlm.nih.gov/pubmed/23084922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.08.010
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