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CD73-generated adenosine facilitates Toxoplasma gondii differentiation to long-lived tissue cysts in the central nervous system

Toxoplasma gondii is an obligate intracellular protozoan pathogen that traffics to the central nervous system (CNS) following invasion of its host. In the CNS, T. gondii undergoes transformation from a rapidly dividing tachyzoite to a long-lived, slow-dividing bradyzoite contained within cysts. The...

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Detalhes bibliográficos
Main Authors: Mahamed, Deeqa A., Mills, Jeffrey H., Egan, Charlotte E., Denkers, Eric Y., Bynoe, Margaret S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479617/
https://ncbi.nlm.nih.gov/pubmed/22988118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205589109
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