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Engineering of blended nanoparticle platform for delivery of mitochondria-acting therapeutics

Mitochondrial dysfunctions cause numerous human disorders. A platform technology based on biodegradable polymers for carrying bioactive molecules to the mitochondrial matrix could be of enormous potential benefit in treating mitochondrial diseases. Here we report a rationally designed mitochondria-t...

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Библиографические подробности
Главные авторы: Marrache, Sean, Dhar, Shanta
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479596/
https://ncbi.nlm.nih.gov/pubmed/22991470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210096109
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