Evidence for additive and interaction effects of host genotype and infection in malaria

The host mechanisms responsible for protection against malaria remain poorly understood, with only a few protective genetic effects mapped in humans. Here, we characterize a host-specific genome-wide signature in whole-blood transcriptomes of Plasmodium falciparum-infected West African children and...

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Bibliographische Detailangaben
Hauptverfasser: Idaghdour, Youssef, Quinlan, Jacklyn, Goulet, Jean-Philippe, Berghout, Joanne, Gbeha, Elias, Bruat, Vanessa, de Malliard, Thibault, Grenier, Jean-Christophe, Gomez, Selma, Gros, Philippe, Rahimy, Mohamed Chérif, Sanni, Ambaliou, Awadalla, Philip
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Feature Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479498/
https://ncbi.nlm.nih.gov/pubmed/22949651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204945109
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