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Inhibitory cross-talk upon introduction of a new metabolic pathway into an existing metabolic network

Evolution or engineering of novel metabolic pathways can endow microbes with new abilities to degrade anthropogenic pollutants or synthesize valuable chemicals. Most studies of the evolution of new pathways have focused on the origins and quality of function of the enzymes involved. However, there i...

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Detalhes bibliográficos
Main Authors: Kim, Juhan, Copley, Shelley D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479479/
https://ncbi.nlm.nih.gov/pubmed/22984162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208509109
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