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Does base-pairing strength play a role in microRNA repression?

MicroRNAs (miRNAs) are short, single-stranded RNAs that silence gene expression by either degrading mRNA or repressing translation. Each miRNA regulates a specific set of mRNA “targets” by binding to complementary sequences in their 3′ untranslated region. In this study, we examined the importance o...

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Bibliografiske detaljer
Main Authors: Carmel, Ido, Shomron, Noam, Heifetz, Yael
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479386/
https://ncbi.nlm.nih.gov/pubmed/23019592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.032185.111
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