Smad8/BMP2–Engineered Mesenchymal Stem Cells Induce Accelerated Recovery of the Biomechanical Properties of the Achilles Tendon

Tendon tissue regeneration is an important goal for orthopedic medicine. We hypothesized that implantation of Smad8/BMP2–engineered MSCs in a full-thickness defect of the Achilles tendon (AT) would induce regeneration of tissue with improved biomechanical properties. A 2 mm defect was created in the...

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Main Authors: Pelled, Gadi, Snedeker, Jess G., Ben-Arav, Ayelet, Rigozzi, Samuela, Zilberman, Yoram, Kimelman-Bleich, Nadav, Gazit, Zulma, Müller, Ralph, Gazit, Dan
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479351/
https://ncbi.nlm.nih.gov/pubmed/22696396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.22167
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