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Role of Cytolethal Distending Toxin in Altered Stool Form and Bowel Phenotypes in a Rat Model of Post-infectious Irritable Bowel Syndrome

BACKGROUND/AIMS: Campylobacter jejuni infection is a leading cause of acute gastroenteritis, which is a trigger for post-infectious irritable bowel syndrome (PI-IBS). Cytolethal distending toxin (CDT) is expressed by enteric pathogens that cause PI-IBS. We used a rat model of PI-IBS to investigate t...

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Main Authors: Pokkunuri, Venkata, Pimentel, Mark, Morales, Walter, Jee, Sam-Ryong, Alpern, Joel, Weitsman, Stacy, Marsh, Zachary, Low, Kimberly, Hwang, Laura, Khoshini, Reza, Barlow, Gillian M, Wang, Hanlin, Chang, Christopher
Format: Artigo
Jezik:Inglês
Izdano: Korean Society of Neurogastroenterology and Motility 2012
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479258/
https://ncbi.nlm.nih.gov/pubmed/23106005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5056/jnm.2012.18.4.434
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