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Ablation of PRMT6 reveals a role as a negative transcriptional regulator of the p53 tumor suppressor
Arginine methylation of histones is a well-known regulator of gene expression. Protein arginine methyltransferase 6 (PRMT6) has been shown to function as a transcriptional repressor by methylating the histone H3 arginine 2 [H3R2(me2a)] repressive mark; however, few targets are known. To define the p...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3479207/ https://ncbi.nlm.nih.gov/pubmed/22904064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks764 |
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