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DNA stabilization at the Bacillus subtilis PolX core—a binding model to coordinate polymerase, AP-endonuclease and 3′-5′ exonuclease activities

Family X DNA polymerases (PolXs) are involved in DNA repair. Their binding to gapped DNAs relies on two conserved helix-hairpin-helix motifs, one located at the 8-kDa domain and the other at the fingers subdomain. Bacterial/archaeal PolXs have a specifically conserved third helix-hairpin-helix motif...

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Main Authors: Baños, Benito, Villar, Laurentino, Salas, Margarita, de Vega, Miguel
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479172/
https://ncbi.nlm.nih.gov/pubmed/22844091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks702
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