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DNA hypomethylation of the COX-2 gene promoter is associated with up-regulation of its mRNA expression in eutopic endometrium of endometriosis

BACKGROUND: Accumulated evidence reveals that cyclooxygenase-2 (COX-2) was overexpressed in eutopic endometrium of endometriosis, which may play a critical role in the pathogenesis of endometriosis. However, few studies have been performed to explore the molecular mechanisms underlying the abnormal...

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Detalhes bibliográficos
Main Authors: Wang, DanBo, Chen, Qi, Zhang, ChiYuan, Ren, Fang, Li, Tong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479074/
https://ncbi.nlm.nih.gov/pubmed/22608095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2047-783X-17-12
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