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Brefeldin A-inhibited Guanine Exchange Factor 2 Regulates Filamin A Phosphorylation and Neuronal Migration

Periventricular heterotopia (PH) is a human malformation of cortical development associated with gene mutations in ADP-ribosylation factor guanine exchange factor 2 (ARFGEF2 encodes for Big2 protein) and Filamin A (FLNA). PH is thought to derive from neuroependymal disruption, but the extent to whic...

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Библиографические подробности
Главные авторы: Zhang, Jingping, Neal, Jason, Lian, Gewei, Shi, Bingxing, Ferland, Russell J., Sheen, Volney
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478955/
https://ncbi.nlm.nih.gov/pubmed/22956851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1063-12.2012
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