Description and validation of high-throughput simultaneous genotyping and mutation scanning by high-resolution melting curve analysis

Mutation scanning using high-resolution melting curve analysis (HR-melt) is an effective and sensitive method to detect sequence variations. However, the presence of a common SNP within a mutation scanning amplicon may considerably complicate the interpretation of results and increase the number of...

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Detalhes bibliográficos
Principais autores: Nguyen-Dumont, Tú, Calvez-Kelm, Florence Le, Forey, Nathalie, McKay-Chopin, Sandrine, Garritano, Sonia, Gioia-Patricola, Lydie, De Silva, Deepika, Weigel, Ron, Sangrajrang, Suleeporn, Lesueur, Fabienne, Tavtigian, Sean V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478947/
https://ncbi.nlm.nih.gov/pubmed/19347964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.20949
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