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Fostering Community Understanding of Sufficient Benefit and Early Stopping for a Phase 2B HIV Prevention Clinical Trial in Africa
BACKGROUND: Most trials of interventions are designed to address the traditional null hypothesis of no benefit. VOICE, a phase 2B HIV prevention trial funded by NIH and conducted in Africa, is designed to assess if the intervention will prevent a substantial fraction of infections. Planned interim a...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3478774/ https://ncbi.nlm.nih.gov/pubmed/21335592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774510387170 |
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