Parathyroid hormone-related protein activates Wnt signaling to specify the embryonic mammary mesenchyme

Parathyroid hormone-related protein (PTHrP) regulates cell fate and specifies the mammary mesenchyme during embryonic development. Loss of PTHrP or its receptor (Pthr1) abolishes the expression of mammary mesenchyme markers and allows mammary bud cells to revert to an epidermal fate. By contrast, ov...

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Bibliographic Details
Main Authors: Hiremath, Minoti, Dann, Pamela, Fischer, Jennifer, Butterworth, Daniela, Boras-Granic, Kata, Hens, Julie, Van Houten, Joshua, Shi, Wei, Wysolmerski, John
Format: Artigo
Language:Inglês
Published: Company of Biologists 2012
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478689/
https://ncbi.nlm.nih.gov/pubmed/23034629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.080671
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