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Parathyroid hormone-related protein activates Wnt signaling to specify the embryonic mammary mesenchyme
Parathyroid hormone-related protein (PTHrP) regulates cell fate and specifies the mammary mesenchyme during embryonic development. Loss of PTHrP or its receptor (Pthr1) abolishes the expression of mammary mesenchyme markers and allows mammary bud cells to revert to an epidermal fate. By contrast, ov...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Company of Biologists
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3478689/ https://ncbi.nlm.nih.gov/pubmed/23034629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.080671 |
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