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Structural and functional insights into alphavirus polyprotein processing and pathogenesis
Alphaviruses, a group of positive-sense RNA viruses, are globally distributed arboviruses capable of causing rash, arthritis, encephalitis, and death in humans. The viral replication machinery consists of four nonstructural proteins (nsP1–4) produced as a single polyprotein. Processing of the polypr...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3478664/ https://ncbi.nlm.nih.gov/pubmed/23010928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210418109 |
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