Toll-like Receptor 4 Deficiency Promotes the Alternative Activation of Adipose Tissue Macrophages

Obesity is characterized by adipose tissue (AT) macrophage (ATM) accumulation, which promotes AT inflammation and dysfunction. Toll-like receptor 4 (TLR4) deficiency attenuates AT inflammation in obesity but does not impede the accumulation of ATMs. The purpose of the current study was to determine...

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Autori principali: Orr, Jeb S., Puglisi, Michael J., Ellacott, Kate L.J., Lumeng, Carey N., Wasserman, David H., Hasty, Alyssa H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2012
Soggetti:
Metabolism
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478520/
https://ncbi.nlm.nih.gov/pubmed/22751700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1595
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