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Impact of Macrophage Toll-Like Receptor 4 Deficiency on Macrophage Infiltration into Adipose Tissue and the Artery Wall in Mice

HYPOTHESIS: Toll-like receptor 4 (TLR4) is a receptor for saturated fatty acids (SFAs) and global deficiency of TLR4 has been shown to protect against inflammation, insulin resistance (IR), and atherosclerotic lesion formation. Because macrophages (Mθs) express TLR4 and are important in IR and ather...

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Detalhes bibliográficos
Main Authors: Coenen, Kimberly R., Gruen, Marnie L., Lee-Young, Robert S., Puglisi, Michael J., Wasserman, David H., Hasty, Alyssa H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615827/
https://ncbi.nlm.nih.gov/pubmed/19052722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-008-1221-7
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