Subcellular trafficking and transfection efficacy of polyethylenimine-polyethylene glycol polyplex nanoparticles with a ligand to melanocortin receptor-1

We have synthesized and investigated properties of new PEI-PEG-based polyplexes containing MC1SP-peptide, a ligand specific for melanocortin receptor-1 (targeted polyplexes), and control polyplexes without this ligand peptide (non-targeted polyplexes). The targeted polyplexes demonstrated receptor-m...

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Main Authors: Durymanov, Mikhail O, Beletkaia, Elena A, Ulasov, Alexey V, Khramtsov, Yuri V, Trusov, Georgiy A, Rodichenko, Nikita S, Slastnikova, Tatiana A, Vinogradova, Tatiana V, Uspenskaya, Natalia Y, Kopantsev, Eugene P, Rosenkranz, Andrey A, Sverdlov, Eugene D, Sobolev, Alexander S
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478489/
https://ncbi.nlm.nih.gov/pubmed/22964392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.08.027
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