Endoplasmic reticulum stress regulates the innate immunity critical transcription factor interferon regulatory factor 3

Interferon regulatory factor 3 (IRF3) regulates early type I IFNs and other genes involved in innate immunity. We have previously shown that cells undergoing an endoplasmic reticulum (ER) stress response called the “Unfolded Protein Response” (UPR) produce synergistically augmented IFN-β when stimul...

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Detalhes bibliográficos
Main Authors: Liu, Yi-Ping, Zeng, Ling, Tian, Austin, Bomkamp, Ashley, Rivera, Daniel, Gutman, Delia, Barber, Glen N., Olson, Julie K., Smith, Judith A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478468/
https://ncbi.nlm.nih.gov/pubmed/23028052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102737
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