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Using epigenetic mechanisms to understand the impact of common disease causing alleles

Many common genetic variants have been identified to be associated with autoimmune diseases such as Type I diabetes. Methods to identify these genetic loci have become powerful, but deciphering the functional effects of these variants in disease progression remains a major challenge. Recent studies...

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Main Authors: Leung, Amy, Schones, Dustin E., Natarajan, Rama
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478440/
https://ncbi.nlm.nih.gov/pubmed/22857822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2012.07.004
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