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Targeting the Genital Tract Mucosa with a Lipopeptide/Recombinant Adenovirus Prime/Boost Vaccine Induces Potent and Long-Lasting CD8(+) T Cell Immunity Against Herpes: Importance of Myeloid Differentiation Factor 88()
Targeting the mucosal immune system of the genital tract (GT) with subunit vaccines failed to induce potent and durable local CD8(+) T cell immunity, crucial for protection against many sexually transmitted viral (STV) pathogens, including herpes simplex virus type 2 (HSV-2) that causes genital herp...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3478413/ https://ncbi.nlm.nih.gov/pubmed/23018456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201121 |
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