Leukotriene B(4) driven neutrophil recruitment to the skin is essential for allergic skin inflammation

Scratching triggers skin flares in atopic dermatitis (AD). We demonstrate that scratching of human skin, and tape stripping of mouse skin, causes neutrophil influx. This influx in mice was largely dependent on the generation of leukotriene B(4) (LTB(4)) by neutrophils and their expression of the LTB...

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Detalhes bibliográficos
Main Authors: Oyoshi, Michiko K., He, Rui, Li, Yitang, Mondal, Subhanjan, Yoon, Juhan, Afshar, Roshi, Chen, Mei, Lee, David M., Luo, Hongbo R., Luster, Andrew D., Cho, John S., Miller, Lloyd S., Larson, Allison, Murphy, George F., Geha, Raif S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478399/
https://ncbi.nlm.nih.gov/pubmed/23063331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.06.018
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