Drosha mediates destabilization of Lin28 mRNA targets

Lin28 plays important roles in development, stem cell maintenance, oncogenesis and metabolism. As an RNA-binding protein, it blocks the biogenesis primarily of let-7 family miRNAs and also promotes translation of a cohort of mRNAs involved in cell growth, metabolism and pluripotency, likely through...

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Detaylı Bibliyografya
Asıl Yazarlar: Qiao, Chong, Ma, Jing, Xu, Jie, Xie, Mingyi, Ma, Wei, Huang, Yingqun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2012
Konular:
Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478310/
https://ncbi.nlm.nih.gov/pubmed/22935707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21871
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