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CEP192 interacts physically and functionally with the K63-deubiquitinase CYLD to promote mitotic spindle assembly
CEP192 is a centrosome protein that plays a critical role in centrosome biogenesis and function in mammals, Drosophila and C. elegans.(1)(-)(6) Moreover, CEP192-depleted cells arrest in mitosis with disorganized microtubules, suggesting that CEP192’s function in spindle assembly goes beyond its role...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Landes Bioscience
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3478306/ https://ncbi.nlm.nih.gov/pubmed/22895009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21574 |
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