Aggregation Behavior of Ibuprofen, cholic acid and dodecylphosphocholine micelles

Non-steroidal anti-inflammatory drugs (NSAIDs) are frequently used to treat chronic pain and inflammation. However, prolonged use of NSAIDs has been known to result in Gastrointestinal (GI) ulceration/bleeding, with a bile-mediated mechanism underlying their toxicity to the lower gut. Bile acids (BA...

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Main Authors: Prakash, Priyanka, Sayyed-Ahmad, Abdallah, Zhou, Yong, Volk, David E., Gorenstein, David G., Dial, Elizabeth, Lichtenberger, Lenard M, Gorfe, Alemayehu A
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478136/
https://ncbi.nlm.nih.gov/pubmed/22885171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2012.07.029
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