Admixture-Matched Case-Control Study: A Practical Approach for Genetic Association Studies in Admixed Populations

Case-control genetic association studies in admixed populations are known to be susceptible to genetic confounding due to population stratification. The transmission/disequilibrium test (TDT) approach can avoid this problem. However, the TDT is expensive and impractical for late- onset diseases. Cas...

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Main Authors: Tsai, Hui-Ju, Kho, Jennifer Y., Shaikh, Nishat, Choudhry, Shweta, Naqvi, Mariam, Navarro, Daniel, Matallana, Henry, Castro, Richard, Lilly, Craig M., Watson, H. George, Meade, Kelley, Le Noir, Michael, Thyne, Shannon, Ziv, Elad, González Burchard, Esteban
Format: Artigo
Sprog:Inglês
Udgivet: 2005
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478103/
https://ncbi.nlm.nih.gov/pubmed/16273390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-005-0080-2
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