Pathway-based genome-wide association analysis of coronary heart disease identifies biologically important gene sets

Genome-wide association (GWA) studies of complex diseases including coronary heart disease (CHD) challenge investigators attempting to identify relevant genetic variants among hundreds of thousands of markers being tested. A selection strategy based purely on statistical significance will result in...

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Hlavní autoři: de las Fuentes, Lisa, Yang, Wei, Dávila-Román, Victor G, Charles Gu, C
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477866/
https://ncbi.nlm.nih.gov/pubmed/22510845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2012.66
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