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In vitro and in vivo protection against indomethacin-induced small intestinal injury by proton pump inhibitors, acid pump antagonists or indomethacin-phosphatidylcholine

BACKGROUND/AIMS: Proton pump inhibitors (PPI) are widely used to prevent NSAID-induced peptic ulcers. NSAIDs produce small intestinal injury and some PPIs have been reported to have a protect against NSAID-induced small bowel injury in rats. To compare PPIs, revaprazan, and phosphatidylcholine-assoc...

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Detalhes bibliográficos
Main Authors: Lim, Yun Jeong, Phan, Tri M, Dial, Elizabeth J, Graham, David Y., Lichtenberger, Lenard M
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477857/
https://ncbi.nlm.nih.gov/pubmed/22907267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000339882
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