Phase II Study of AZD2171 in Patients with Malignant Pleural Mesothelioma: SWOG S0509

BACKGROUND: Malignant pleural mesothelioma (MPM) tumors express VEGF and VEGF receptors. MPM patients have high circulating levels of VEGF, suggesting that tumor angiogenesis is a relevant therapeutic target for MPM. We conducted a phase 2 trial of the VEGFR1/2 TKI AZD2171 in patients with MPM after...

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Main Authors: Garland, Linda L., Chansky, Kari, Wozniak, Antoinette J., Tsao, Anne S., Gadgeel, Shirish M., Verschraegen, Claire F., DaSilva, Marco A., Redman, Mary, Gandara, David R.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477852/
https://ncbi.nlm.nih.gov/pubmed/21964533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e318229586e
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