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Degradation Pathway for Eplerenone by Validated Stability Indicating UP-LC Method

Degradation pathway for eplerenone is established as per ICH recommendations by validated and stability-indicating reverse phase liquid chromatographic method. Eplerenone is subjected to stress conditions of acid, base, oxidation, and thermal and photolysis. Significant degradation is observed in ac...

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Main Authors: Sudhakar Babu, Kondru, Madireddy, Venkataramanna, Indukuri, Venkata Somaraju
Format: Artigo
Jezik:Inglês
Izdano: International Scholarly Research Network 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477670/
https://ncbi.nlm.nih.gov/pubmed/23097723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5402/2012/251247
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