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Phase I/II Trial of the Anti-HIV Activity of Mifepristone in HIV-Infected Subjects ACTG 5200

BACKGROUND: Mifepristone is a glucocorticoid receptor inhibitor shown in vitro to have anti-HIV activity and anti-simian immunodeficiency virus activity in a macaque model. A phase I/II trial was performed to assess the drug’s safety and anti-HIV activity. METHODS: A 28-day double-blind, placebo-con...

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Detalhes bibliográficos
Main Authors: Para, Michael F., Schouten, Jeff, Rosenkranz, Susan L., Yu, Song, Weiner, David, Tebas, Pablo, White, C. Jo, Reeds, Dominic, Lertora, Juan, Patterson, Kristine B., Daar, Eric S., Cavert, Wintson, Brizz, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477637/
https://ncbi.nlm.nih.gov/pubmed/20130470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e3181d142cb
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