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Suppression of Aldosterone Synthesis and Secretion by Ca(2+) Channel Antagonists

Aldosterone, a specific mineralocorticoid receptor (MR) agonist and a key player in the development of hypertension, is synthesized as a final product of renin-angiotensin-aldosterone system. Hypertension can be generally treated by negating the effects of angiotensin II through the use of angiotens...

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Main Authors: Ikeda, Keiichi, Isaka, Tsuyoshi, Fujioka, Kouki, Manome, Yoshinobu, Tojo, Katsuyoshi
格式: Artigo
語言:Inglês
出版: Hindawi Publishing Corporation 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477571/
https://ncbi.nlm.nih.gov/pubmed/23097668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/519467
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