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Contrast-Enhanced Functional Blood Volume Imaging (CE-fBVI): Enhanced Sensitivity for Brain Activation in Humans using the Ultrasmall Superparamagnetic Iron Oxide Agent Ferumoxytol
Functional MRI (fMRI) brain studies performed in the presence of a steady-state or “blood pool” contrast agent yields activation maps that are weighted for cerebral blood volume (CBV). Previous animal experiments suggest significant contrast-to-noise (CNR) improvements, but these studies have not ye...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3477511/ https://ncbi.nlm.nih.gov/pubmed/22584230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2012.05.010 |
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