Contrast-Enhanced Functional Blood Volume Imaging (CE-fBVI): Enhanced Sensitivity for Brain Activation in Humans using the Ultrasmall Superparamagnetic Iron Oxide Agent Ferumoxytol

Functional MRI (fMRI) brain studies performed in the presence of a steady-state or “blood pool” contrast agent yields activation maps that are weighted for cerebral blood volume (CBV). Previous animal experiments suggest significant contrast-to-noise (CNR) improvements, but these studies have not ye...

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Hauptverfasser: Qiu, Deqiang, Zaharchuk, Greg, Christen, Thomas, Ni, Wendy W, Moseley, Michael E
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477511/
https://ncbi.nlm.nih.gov/pubmed/22584230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2012.05.010
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