Obesity resistant S5B rats showed greater cocaine conditioned place preference than the obesity prone OM rats

BACKGROUND: Dopamine (DA) and the DA D2 receptor (D2R) are involved in the rewarding and the conditioned responses to food and drug rewards. Osborne-Mendel (OM) rats are genetically prone and S5B/P rats are genetically resistant to obesity when fed a high-fat diet. We hypothesized that the different...

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Main Authors: Thanos, Panayotis K., Kim, Ronald, Cho, Jacob, Michaelides, Michael, Anderson, Brenda J., Primeaux, Stefany D., Bray, George A., Wang, Gene-Jack, Robinson, John K., Volkow, Nora D.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477469/
https://ncbi.nlm.nih.gov/pubmed/20801137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.physbeh.2010.08.011
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