Population pharmacokinetics of mycophenolic acid and dose optimization with limited sampling strategy in liver transplant children

AIMS: The aims were to estimate the mycophenolic acid (MPA) population pharmacokinetic parameters in paediatric liver transplant recipients, to identify the factors affecting MPA pharmacokinetics and to develop a limited sampling strategy to estimate individual MPA AUC(0,12 h). METHODS: Twenty-eight...

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Bibliografiske detaljer
Main Authors: Barau, Caroline, Furlan, Valérie, Debray, Dominique, Taburet, Anne-Marie, Barrail-Tran, Aurélie
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2012
Fag:
Paediatric Clinical Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477353/
https://ncbi.nlm.nih.gov/pubmed/22329639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2012.04213.x
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