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Embryonic expression of AMPK γ subunits and the identification of a novel γ2 transcript variant in adult heart
AMP-activated protein kinase (AMPK), the key sensor and regulator of cellular energy status, is a heterotrimeric enzyme with multiple isoforms for each subunit (α1/α 2; β1/β2; γ1/γ2/γ3). Mutations in PRKAG2, which encodes the γ2 regulatory subunit, cause a cardiomyopathy characterized by hypertrophy...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Academic Press
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3477313/ https://ncbi.nlm.nih.gov/pubmed/22683324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2012.05.017 |
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