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Modification of anxiety-like behaviors by nociceptin/orphanin FQ (N/OFQ) and time-dependent changes in N/OFQ-NOP gene expression following ethanol withdrawal
Anxiety is a key consequence of ethanol withdrawal and important risk factor for relapse. The neuropeptide nociceptin/orphanin FQ (N/OFQ), or agonists at this peptide’s receptor (NOP), exert anxiolytic-like and anti-stress actions. N/OFQ dysfunction has been linked to both a high-anxiety behavioral...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3477306/ https://ncbi.nlm.nih.gov/pubmed/22804785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1369-1600.2012.00466.x |
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