Modification of anxiety-like behaviors by nociceptin/orphanin FQ (N/OFQ) and time-dependent changes in N/OFQ-NOP gene expression following ethanol withdrawal

Anxiety is a key consequence of ethanol withdrawal and important risk factor for relapse. The neuropeptide nociceptin/orphanin FQ (N/OFQ), or agonists at this peptide’s receptor (NOP), exert anxiolytic-like and anti-stress actions. N/OFQ dysfunction has been linked to both a high-anxiety behavioral...

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Bibliografiske detaljer
Main Authors: Aujla, H, Cannarsa, R, Romualdi, P, Ciccocioppo, R, Martin-Fardon, R, Weiss, F
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477306/
https://ncbi.nlm.nih.gov/pubmed/22804785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1369-1600.2012.00466.x
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