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Aryl Hydrocarbon Receptor (AHR)-Active Pharmaceuticals Are Selective AHR Modulators in MDA-MB-468 and BT474 Breast Cancer Cells

Leflunomide, flutamide, nimodipine, mexiletine, sulindac, tranilast, 4-hydroxytamoxifen, and omeprazole are pharmaceuticals previously characterized as aryl hydrocarbon receptor (AHR) agonists in various cell lines and animal models. In this study, the eight AHR-active pharmaceuticals were investiga...

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Библиографические подробности
Главные авторы: Jin, Un-Ho, Lee, Syng-ook, Safe, Stephen
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Pharmacology and Experimental Therapeutics 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477220/
https://ncbi.nlm.nih.gov/pubmed/22879383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.195339
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