APE1/Ref-1 Regulates STAT3 Transcriptional Activity and APE1/Ref-1–STAT3 Dual-Targeting Effectively Inhibits Pancreatic Cancer Cell Survival

Pancreatic cancer is a largely incurable disease, and increasing evidence supports strategies targeting multiple molecular mediators of critical functions of pancreatic ductal adenocarcinoma cells. Intracellular redox state modulates the activity of various signal transduction pathways and biologica...

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Detaylı Bibliyografya
Asıl Yazarlar: Cardoso, Angelo A., Jiang, Yanlin, Luo, Meihua, Reed, April M., Shahda, Safi, He, Ying, Maitra, Anirban, Kelley, Mark R., Fishel, Melissa L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477158/
https://ncbi.nlm.nih.gov/pubmed/23094050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047462
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