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Genomic Expression Analyses Reveal Lysosomal, Innate Immunity Proteins, as Disease Correlates in Murine Models of a Lysosomal Storage Disorder

Niemann-Pick Type C (NPC) disease is a rare, genetic, lysosomal disorder with progressive neurodegeneration. Poor understanding of the pathophysiology and a lack of blood-based diagnostic markers are major hurdles in the treatment and management of NPC and several additional, neurological lysosomal...

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Detalhes bibliográficos
Main Authors: Alam, Md. Suhail, Getz, Michelle, Safeukui, Innocent, Yi, Sue, Tamez, Pamela, Shin, Jenny, Velázquez, Peter, Haldar, Kasturi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477142/
https://ncbi.nlm.nih.gov/pubmed/23094108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048273
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