Improving metabolic flux predictions using absolute gene expression data

BACKGROUND: Constraint-based analysis of genome-scale metabolic models typically relies upon maximisation of a cellular objective function such as the rate or efficiency of biomass production. Whilst this assumption may be valid in the case of microorganisms growing under certain conditions, it is l...

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Detaylı Bibliyografya
Asıl Yazarlar: Lee, Dave, Smallbone, Kieran, Dunn, Warwick B, Murabito, Ettore, Winder, Catherine L, Kell, Douglas B, Mendes, Pedro, Swainston, Neil
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2012
Konular:
Methodology Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477026/
https://ncbi.nlm.nih.gov/pubmed/22713172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-73
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