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Vascular endothelial growth factor A, secreted in response to transforming growth factor-β1 under hypoxic conditions, induces autocrine effects on migration of prostate cancer cells

Hypoxia and transforming growth factor-β1 (TGF-β1) increase vascular endothelial growth factor A (VEGFA) expression in a number of malignancies. This effect of hypoxia and TGF-β1 might be responsible for tumor progression and metastasis of advanced prostate cancer. In the present study, TGF-β1 was s...

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Detalhes bibliográficos
Main Authors: Darrington, Eric, Zhong, Miao, Vo, Bao-Han, Khan, Shafiq A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476842/
https://ncbi.nlm.nih.gov/pubmed/22705563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aja.2011.197
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