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In Vivo Biodistribution and Pharmacokinetics of Silica Nanoparticles as a Function of Geometry, Porosity and Surface Characteristics

The in vivo biodistribution and pharmacokinetics of silica nanoparticles (SiO(2)) with systematically varied geometries, porosities, and surface characteristics were investigated in immune-competent CD-1 mice via the intravenous injection. The nanoparticles were taken up extensively by the liver and...

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Detalhes bibliográficos
Main Authors: Yu, Tian, Hubbard, Dallin, Ray, Abhijit, Ghandehari, Hamidreza
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476833/
https://ncbi.nlm.nih.gov/pubmed/22684119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.05.046
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