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Stimulation of Resistance of Immunocompromised Mice by a Muramyl Dipeptide Analog

L18-MDP(Ala), a synthetic derivative of muramyl dipeptide, enhanced resistance against Escherichia coli and Candida albicans infections in aged mice and younger adult mice whose defense mechanism(s) had been depressed by X-ray irradiation or by treatment with cyclophosphamide.

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Bibliographic Details
Main Authors: Osada, Yasuaki, Mitsuyama, Masao, Matsumoto, Kensuke, Une, Tsutomu, Otani, Tsuyoshi, Ogawa, Hidemasa, Nomoto, Kikuo
Format: Artigo
Language:Inglês
Published: 1982
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC347677/
https://ncbi.nlm.nih.gov/pubmed/6752024
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